B. Usha Priya and V. Lokeswara Reddy
Adv. Artif. Intell. Mach. Learn., XX (XX):-
1. B. Usha Priya: JNTUA
2. V. Lokeswara Reddy: JNTUA
DOI: 10.54364/AAIML.2026.62299
Article History: Received on: 05-Jan-26, Accepted on: 21-Apr-26, Published on: 28-Apr-26
Corresponding Author: B. Usha Priya
Email: ushapriya512@gmail.com
Citation: Usha Priya and V. Lokeswara Reddy. A Robust Hybrid Framework for Lung Nodule Detection and Clas- sification from CT Images. Advances in Artificial Intelligence and Machine Learning. 2026. (Ahead of Print). https://dx.doi.org/10.54364/AAIML.2026.62299
Introduction/Objective: Early identification of lung cancer can save
lives and reduce mortality. Existing methods struggle to jointly capture local
features, global relationships, and temporal changes, limiting reliable lung
nodule detection and classification.
Methods: This study
presents NoduleVision-Net, a hybrid deep learning framework that can aid in the
future potential detection of lung cancer in its early and clinically relevant
stages. Following the extraction of clean and consistent input data through the
preprocessing steps of Non-Local Means filtering and brightness normalization,
the framework merges convolutional-based modules that extract local features
with transformer-based modules that understand a global context, while temporal
modeling can understand patterns of nodule growth and development over time.
The Nodule-Net framework creates a bridge between local and global
representations and ultimately provides a novel, robust, and clinically
interpretable approach for detecting and classifying lung nodules.
Results: The Nodule-Net
model demonstrated superior performance in lung cancer classification, attaining
99.98 % accuracy, precision, recall, and F1-score on the Chest CT dataset. It
surpasses existing approaches while enhancing predictive reliability and
reducing computational demands.
Discussion: This proposed model demonstrates its robust
performance in lung cancer detection by combining high accuracy with
computational efficiency. Its high precision and reduced complexity outperform
prior methods by enhancing early diagnosis, informing clinical decision-making,
and advancing automated imaging analysis in medical practice.
Conclusion: This model, with high accuracy, precision, and
reduced complexity in lung cancer classification, outperforms traditional
methods by enhancing early diagnosis, informing clinical decision-making, and
advancing automated imaging analysis in medical practice.